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  <xsd:element id="agnc_InterestRateDerivativeNotDesignatedAsHedgingInstrumentsReceiveRate" name="InterestRateDerivativeNotDesignatedAsHedgingInstrumentsReceiveRate" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="agnc_InterestRateSwapsExcludingForwardStartingMember" name="InterestRateSwapsExcludingForwardStartingMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="agnc_InterestRateSwapsMember" name="InterestRateSwapsMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_InvestmentInAgencySecuritiesTextBlock" name="InvestmentInAgencySecuritiesTextBlock" nillable="true" substitutionGroup="xbrli:item" type="nonnum:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="agnc_LessThanOrEqualToOneYearMember" name="LessThanOrEqualToOneYearMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="agnc_LongtermCapitalGainMember" name="LongtermCapitalGainMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_LossOnDerivativeInstrumentsAndTradingSecuritiesNet" name="LossOnDerivativeInstrumentsAndTradingSecuritiesNet" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element id="agnc_LossOnInterestOnlySecuritiesRemeasuredAtFairValueThroughEarnings" name="LossOnInterestOnlySecuritiesRemeasuredAtFairValueThroughEarnings" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="agnc_ManagementAgreementAbstract" name="ManagementAgreementAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="agnc_MarkitIosTotalReturnSwapsLongMember" name="MarkitIosTotalReturnSwapsLongMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="agnc_MarkitIosTotalReturnSwapsShortMember" name="MarkitIosTotalReturnSwapsShortMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="agnc_Maturity31To59DaysMember" name="Maturity31To59DaysMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="agnc_Maturity60To90DaysMember" name="Maturity60To90DaysMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_NetAmountAfterDeductingGrossAmountsNotOffsetOnBalanceSheetFromNetAmountOfAssetsLiabilitiesPresentedOnBalanceSheet" name="NetAmountAfterDeductingGrossAmountsNotOffsetOnBalanceSheetFromNetAmountOfAssetsLiabilitiesPresentedOnBalanceSheet" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:periodType="instant" />
  <xsd:element id="agnc_NetAmountOfAssetsLiabilitiesPresentedOnBalanceSheet" name="NetAmountOfAssetsLiabilitiesPresentedOnBalanceSheet" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:periodType="instant" />
  <xsd:element id="agnc_NetCurrentPeriodOtherComprehensiveIncome" name="NetCurrentPeriodOtherComprehensiveIncome" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element id="agnc_NetPeriodicInterestRateCostsOnSwaps" name="NetPeriodicInterestRateCostsOnSwaps" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="agnc_NotionalAdditionsDuringthePeriodMember" name="NotionalAdditionsDuringthePeriodMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_NotionalAmountOfCashFlowHedgeInstrumentsAdditionsDuringPeriod" name="NotionalAmountOfCashFlowHedgeInstrumentsAdditionsDuringPeriod" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element id="agnc_NotionalAmountOfCashFlowHedgeInstrumentsSettlementsExpirationsDuringPeriod" name="NotionalAmountOfCashFlowHedgeInstrumentsSettlementsExpirationsDuringPeriod" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element id="agnc_NotionalAmountOfDerivativesNotDesignatedAsHedgingInstrumentsAdditionsDueToHedgeDeDesignations" name="NotionalAmountOfDerivativesNotDesignatedAsHedgingInstrumentsAdditionsDueToHedgeDeDesignations" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element id="agnc_NotionalAmountOfDerivativesNotDesignatedAsHedgingInstrumentsAdditionsDuringPeriod" name="NotionalAmountOfDerivativesNotDesignatedAsHedgingInstrumentsAdditionsDuringPeriod" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element id="agnc_NotionalAmountOfDerivativesNotDesignatedAsHedgingInstrumentsSettlementExpirationDuringPeriod" name="NotionalAmountOfDerivativesNotDesignatedAsHedgingInstrumentsSettlementExpirationDuringPeriod" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element id="agnc_NotionalAmountOfTradingSecuritiesSettlementExpirationDuringThePeriod" name="NotionalAmountOfTradingSecuritiesSettlementExpirationDuringThePeriod" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="agnc_NotionalTerminationsExpirationsDuringthePeriodMemberMember" name="NotionalTerminationsExpirationsDuringthePeriodMemberMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_ObligationToReturnSecuritiesBorrowedUnderReverseRepurchaseAgreementsAtFairValue" name="ObligationToReturnSecuritiesBorrowedUnderReverseRepurchaseAgreementsAtFairValue" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element abstract="true" id="agnc_OffsettingAssetsAndLiabilitiesAbstract" name="OffsettingAssetsAndLiabilitiesAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="agnc_OffsettingAssetsAndLiabilitiesLineItems" name="OffsettingAssetsAndLiabilitiesLineItems" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="agnc_OffsettingAssetsAndLiabilitiesTable" name="OffsettingAssetsAndLiabilitiesTable" nillable="true" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="agnc_OffsettingOfFinancialAssetsAndLiabilitiesAxis" name="OffsettingOfFinancialAssetsAndLiabilitiesAxis" nillable="true" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_OptionsAtCost" name="OptionsAtCost" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="agnc_OrdinaryIncomePerShareMember" name="OrdinaryIncomePerShareMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="agnc_OrganizationAbstract" name="OrganizationAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_OtherComprehensiveIncomeReclassificationAdjustmentForSaleOfSecurityReversalOfPriorPeriodUnrealizedGainAndLossesOnRealization" name="OtherComprehensiveIncomeReclassificationAdjustmentForSaleOfSecurityReversalOfPriorPeriodUnrealizedGainAndLossesOnRealization" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element id="agnc_OtherDebtNetOfDiscounts" name="OtherDebtNetOfDiscounts" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element abstract="true" id="agnc_OtherDerivativesMember" name="OtherDerivativesMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_OtherRealizedGainLossOnDerivativeInstrumentsAndOtherSecuritiesNet" name="OtherRealizedGainLossOnDerivativeInstrumentsAndOtherSecuritiesNet" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="agnc_PayerSwaptionMember" name="PayerSwaptionMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="agnc_PledgedAssetsAbstract" name="PledgedAssetsAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_PledgedAssetsTextBlock" name="PledgedAssetsTextBlock" nillable="true" substitutionGroup="xbrli:item" type="nonnum:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_PrefdStockLiquidationPreference" name="PrefdStockLiquidationPreference" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element id="agnc_PreferredStock7.750SeriesBValueIssued" name="PreferredStock7.750SeriesBValueIssued" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element id="agnc_PreferredStockAuthorizedButNotIssued" name="PreferredStockAuthorizedButNotIssued" nillable="true" substitutionGroup="xbrli:item" type="xbrli:sharesItemType" xbrli:periodType="instant" />
  <xsd:element id="agnc_PrincipalBalanceOfSecuritiesHeldAsCollateral" name="PrincipalBalanceOfSecuritiesHeldAsCollateral" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element id="agnc_ProceedsFromPrincipalCollectionOfMortgageBackedSecuritiesCategorizedAsAvailableForSale" name="ProceedsFromPrincipalCollectionOfMortgageBackedSecuritiesCategorizedAsAvailableForSale" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="agnc_PurchasesOfTbasAndForwardSettlingAgencySecuritiesMember" name="PurchasesOfTbasAndForwardSettlingAgencySecuritiesMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="agnc_QualifiedDividendsPerShareMember" name="QualifiedDividendsPerShareMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_ReceivableUnderReverseRepurchaseAgreements" name="ReceivableUnderReverseRepurchaseAgreements" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element abstract="true" id="agnc_ReceiverInterestRateSwapsMember" name="ReceiverInterestRateSwapsMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="agnc_ReceiverSwaptionMember" name="ReceiverSwaptionMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_RepurchaseAgreementsWeightedAverageDaysToMaturity" name="RepurchaseAgreementsWeightedAverageDaysToMaturity" nillable="true" substitutionGroup="xbrli:item" type="xbrli:decimalItemType" xbrli:periodType="instant" />
  <xsd:element id="agnc_RequiredAnnualDistributionOfTaxableNetIncome" name="RequiredAnnualDistributionOfTaxableNetIncome" nillable="true" substitutionGroup="xbrli:item" type="num:percentItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_RestrictedCashandSecuritiesPledged" name="RestrictedCashandSecuritiesPledged" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element abstract="true" id="agnc_ReverseRepurchaseAgreementsMember" name="ReverseRepurchaseAgreementsMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_ReverseRepurchaseAgreementsPolicyPolicyTextBlock" name="ReverseRepurchaseAgreementsPolicyPolicyTextBlock" nillable="true" substitutionGroup="xbrli:item" type="nonnum:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_RiskOfRepurchaseAgreementToStockholdersEquity" name="RiskOfRepurchaseAgreementToStockholdersEquity" nillable="true" substitutionGroup="xbrli:item" type="num:percentItemType" xbrli:periodType="instant" />
  <xsd:element abstract="true" id="agnc_SaleOfTbaAndForwardSettlingAgencySecuritiesMember" name="SaleOfTbaAndForwardSettlingAgencySecuritiesMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_ScheduleOfBorrowingsUnderRepurchaseAgreementsAndWeightedAverageInterestRatesTableTextBlock" name="ScheduleOfBorrowingsUnderRepurchaseAgreementsAndWeightedAverageInterestRatesTableTextBlock" nillable="true" substitutionGroup="xbrli:item" type="nonnum:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_ScheduleOfInterestRateSwapAgreementByRemainingMaturityTableTextBlock" name="ScheduleOfInterestRateSwapAgreementByRemainingMaturityTableTextBlock" nillable="true" substitutionGroup="xbrli:item" type="nonnum:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_ScheduleOfInterestRateSwaptionAgreementsOutstandinTableTextBlock" name="ScheduleOfInterestRateSwaptionAgreementsOutstandinTableTextBlock" nillable="true" substitutionGroup="xbrli:item" type="nonnum:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_ScheduleOfLongAndShortPositionOfDerivativeInstrumentsTableTextBlock" name="ScheduleOfLongAndShortPositionOfDerivativeInstrumentsTableTextBlock" nillable="true" substitutionGroup="xbrli:item" type="nonnum:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_ScheduleOfOutstandingDerivativesNotDesignatedAsHedgingInstrumentsTableTextBlock" name="ScheduleOfOutstandingDerivativesNotDesignatedAsHedgingInstrumentsTableTextBlock" nillable="true" substitutionGroup="xbrli:item" type="nonnum:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_ScheduleOfOutstandingNotDesignatedAsHedgingInstrumentsTableTextBlock" name="ScheduleOfOutstandingNotDesignatedAsHedgingInstrumentsTableTextBlock" nillable="true" substitutionGroup="xbrli:item" type="nonnum:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="agnc_ScheduleofDividendsPaidLineItems" name="ScheduleofDividendsPaidLineItems" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="agnc_ScheduleofDividendsPaidTable" name="ScheduleofDividendsPaidTable" nillable="true" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_ScheduleofSecuritiesandCashPledgedasCollateralfromCounterpartiesTableTextBlock" name="ScheduleofSecuritiesandCashPledgedasCollateralfromCounterpartiesTableTextBlock" nillable="true" substitutionGroup="xbrli:item" type="nonnum:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_SchedulesOfSecuritiesPledgedAsCollateralUnderRepurchaseAgreementTextBlockTableTextBlock" name="SchedulesOfSecuritiesPledgedAsCollateralUnderRepurchaseAgreementTextBlockTableTextBlock" nillable="true" substitutionGroup="xbrli:item" type="nonnum:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_SecuritizedCmoSecurities" name="SecuritizedCmoSecurities" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element id="agnc_SpreadOverLibor" name="SpreadOverLibor" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="agnc_StockholdersEquityTable" name="StockholdersEquityTable" nillable="true" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_SummaryOfAgencySecuritiesEstimatedWeightedAverageLifeClassificationsTableTextBlock" name="SummaryOfAgencySecuritiesEstimatedWeightedAverageLifeClassificationsTableTextBlock" nillable="true" substitutionGroup="xbrli:item" type="nonnum:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_SummaryOfChangesInAccumulatedOciForAgencySecuritieTableTextBlock" name="SummaryOfChangesInAccumulatedOciForAgencySecuritieTableTextBlock" nillable="true" substitutionGroup="xbrli:item" type="nonnum:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_SummaryOfContinuousUnrealizedLossPositionOfAvailableForSaleSecuritiesTableTextBlock" name="SummaryOfContinuousUnrealizedLossPositionOfAvailableForSaleSecuritiesTableTextBlock" nillable="true" substitutionGroup="xbrli:item" type="nonnum:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_SummaryOfNetGainFromSaleOfAgencySecuritiesTableTextBlock" name="SummaryOfNetGainFromSaleOfAgencySecuritiesTableTextBlock" nillable="true" substitutionGroup="xbrli:item" type="nonnum:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="agnc_TBAandForwardSettlingAgencySecuritiesMember" name="TBAandForwardSettlingAgencySecuritiesMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="agnc_TaxCharacterizationAxis" name="TaxCharacterizationAxis" nillable="true" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="agnc_TaxCharacterizationDomain" name="TaxCharacterizationDomain" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="agnc_TbaSecuritiesFifteenYearAndThirtyYearSecuritiesMember" name="TbaSecuritiesFifteenYearAndThirtyYearSecuritiesMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="agnc_ThirtyOneToNinetyMember" name="ThirtyOneToNinetyMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_TotalAgencySecurities" name="TotalAgencySecurities" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element id="agnc_TotalFairValueOfAgencySecuritiesPledgedAndAccruedInterest" name="TotalFairValueOfAgencySecuritiesPledgedAndAccruedInterest" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element id="agnc_TotalReclassOfOtherComprehensiveIncome" name="TotalReclassOfOtherComprehensiveIncome" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element id="agnc_TradingSecuritiesAddedDuringthePeriod" name="TradingSecuritiesAddedDuringthePeriod" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element id="agnc_TransfersBetweenHierarchyLevels" name="TransfersBetweenHierarchyLevels" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="agnc_TreasuryFuturesMember" name="TreasuryFuturesMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="agnc_TreasuryFuturesShortMember" name="TreasuryFuturesShortMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_UnamortizedPrincipalBalanceOfInterestOnlyStrips" name="UnamortizedPrincipalBalanceOfInterestOnlyStrips" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element id="agnc_UnamortizedPrincipalBalanceOfPrincipalOnlyStrips" name="UnamortizedPrincipalBalanceOfPrincipalOnlyStrips" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="agnc_UnderPrimeBrokerAgreementsMember" name="UnderPrimeBrokerAgreementsMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_UndistributedTaxableIncome" name="UndistributedTaxableIncome" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element id="agnc_UnrealizedGainOnDerivatives" name="UnrealizedGainOnDerivatives" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element id="agnc_UnrealizedLossOnDerivatives" name="UnrealizedLossOnDerivatives" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element id="agnc_WeightedAverageContractualInterestRateOfInterestOnlyStrips" name="WeightedAverageContractualInterestRateOfInterestOnlyStrips" nillable="true" substitutionGroup="xbrli:item" type="num:percentItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_WeightedAverageLifeInterestOnlySecurities" name="WeightedAverageLifeInterestOnlySecurities" nillable="true" substitutionGroup="xbrli:item" type="xbrli:durationItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_WeightedAverageLifeOfInterestOnlySecurities" name="WeightedAverageLifeOfInterestOnlySecurities" nillable="true" substitutionGroup="xbrli:item" type="xbrli:decimalItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_WeightedAverageLifeOfPrincipalOnlySecurities" name="WeightedAverageLifeOfPrincipalOnlySecurities" nillable="true" substitutionGroup="xbrli:item" type="xbrli:decimalItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_WeightedAverageLifeOtherDebt" name="WeightedAverageLifeOtherDebt" nillable="true" substitutionGroup="xbrli:item" type="xbrli:durationItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_WeightedAverageLifePrincipalOnlySecurities" name="WeightedAverageLifePrincipalOnlySecurities" nillable="true" substitutionGroup="xbrli:item" type="xbrli:durationItemType" xbrli:periodType="duration" />
  <xsd:element id="agnc_WeightedAverageYieldPercentage" name="WeightedAverageYieldPercentage" nillable="true" substitutionGroup="xbrli:item" type="num:percentItemType" xbrli:periodType="instant" />
  <xsd:element id="agnc_WeightedAverageYieldPercentageForPeriod" name="WeightedAverageYieldPercentageForPeriod" nillable="true" substitutionGroup="xbrli:item" type="num:percentItemType" xbrli:periodType="duration" />
</xsd:schema>
