Press Release

BETHESDA, Md., April 24, 2012 /PRNewswire via COMTEX/ --American Capital Agency Corp. (Nasdaq: AGNC) ("AGNC" or the "Company") announced today it will report first quarter 2012 earnings after market close on May 2, 2012. AGNC invites shareholders, prospective shareholders and analysts to attend the AGNC shareholder call on May 3, 2012 at 11:00 am ET. The call can be accessed through a live webcast, free of charge, at http://www.agnc.com/ or by dialing (877) 270-2148 (U.S. domestic) or (412) 902-6510 (international). Please advise the operator you are dialing in for the American Capital Agency shareholder call. If you do not plan on asking a question on the call and have access to the internet, please take advantage of the webcast.

A slide presentation will accompany the call and will be available at http://www.agnc.com/. Select the Q1 2012 Earnings Presentation link to download and print the presentation in advance of the shareholder call.

An archived audio of the shareholder call combined with the slide presentation will be made available on the AGNC website after the call on May 3. In addition, there will be a phone recording available from 2:00 pm ET May 3 until 9:00 am ET May 18. If you are interested in hearing the recording of the presentation, please dial (877) 344-7529 (U.S. domestic) or (412) 317-0088 (international). The conference number is 10013452.

For further information or questions, please contact our Investor Relations Department at (301) 968-9300 or [email protected].

ABOUT AMERICAN CAPITAL AGENCY CORP.

American Capital Agency Corp. is a real estate investment trust that invests in agency pass-through securities and collateralized mortgage obligations for which the principal and interest payments are guaranteed by a U.S. Government agency or a U.S. Government-sponsored entity. The Company is externally managed and advised by American Capital AGNC Management, LLC, an affiliate of American Capital, Ltd. ("American Capital"). For further information, please refer to http://www.agnc.com/.

ABOUT AMERICAN CAPITAL

American Capital is a publicly traded private equity firm and global asset manager. American Capital, both directly and through its asset management business, originates, underwrites and manages investments in middle market private equity, leveraged finance, real estate and structured products. American Capital has $68 billion in assets under management as of December 31, 2011 and seven offices in the U.S. and Europe. American Capital and European Capital will consider investment opportunities from $10 million to $500 million. For further information, please refer to http://www.americancapital.com/.

CONTACT:
Investors - (301) 968-9300

SOURCE American Capital Agency Corp.